· Persistently elevated liver enzymes may be caused by certain types of cancer, including liver, colon, breast, stomach, pancreas, and skin cancers. Liver enzymes are proteins produced by your... · Several cancers can raise liverenzymes, particularly those that begin in the liver or spread to it. This includes hepatocellular carcinoma (HCC, which is the main form of primary livercancer) and cancers such as colorectal, breast, lung, pancreatic, stomach, esophageal, melanoma, and neuroendocrine tumors that often spread (metastasize) to ... · Primary livercancer, which begins in the liver, can cause abnormal liverenzymes. Colorectal cancer is the most common secondary or metastatic cause of liver tumors. · Tumors with high metabolic activity, such as hepatocellular carcinoma (HCC) or metastatic liver disease, can cause hepatocytes to undergo stress-induced apoptosis or necrosis, releasing intracellular enzymes into the bloodstream. Liver enzyme abnormalities are often seen in cancers that directly affect the liver such as hepatocellular carcinoma and cholangiocarcinoma. Metastatic cancers, particularly those originating from the colon, breast, lung, or pancreas, can also lead to elevated liver enzymes. · Many diseases, medications and conditions can causeelevatedliverenzymes. Your healthcare team will review your medicines and symptoms and sometimes prescribe other tests and procedures to find the cause. This comprehensive guide explores the connection between elevatedliverenzymes and cancer, including warning signs, diagnostic processes, and other potential causes of abnormal liverenzyme levels.
